Posts tagged as 'pharmaceutical supply chain'

Supply chain agility, the disillusioned data scientist, Amazon effect, and other tales from LogiPharma US 2017

Dr. MadhavDurbha

LogiPharma - Pharmaceutical supply chainI was at the recent LogiPharma US conference for the pharmaceutical supply chain leaders. However, most of the insights and the stories I took away from the event are applicable to other industries as well. Here they are:

1. Personalized medicine demands supply chain agility: During a highly engaging panel discussion on “Building a patient-centric supply chain”, Kevin Cook, VP of North America supply chain at Sandoz (a division of Novartis) talked about the unique nature of the recently approved Kymriah, CAR-T cell therapy for children and young adults with certain types of Leukemia. The therapy showed an 83% remission rate in the patient population studied! In CAR-T cell therapy, every single dose of a treatment is completely personalized, as it involves extracting the patient’s immune cells, bringing them to a production facility, genetically modifying them, transporting them back (at minus 180oF!!), and then reinfusing the patient to fight the cancer cells. So, personalized medicine is here! With it comes several logistical challenges.

While Kymriah is the ultimate example of personalized therapy, there were several attending companies that provided therapies for rare diseases affecting a few hundred to a few thousand patients across the globe. In such a high mix, low volume portfolio, decisions such as how to allocate short supply to patients in case of contamination of a manufactured batch, can be lifesaving. Brad Pawlowski of Accenture said it right during his opening remarks – “Instead of executing one supply chain a thousand times, we should get ready to execute a thousand supply chains, one at a time”.

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[Video] Sanofi Genzyme trends in pharmaceutical supply chains

MelissaClow

This blog is part of a video interview series. Check out the video below as well as links to other supply chain practitioner and Kinaxis executive interviews.

Merging two companies is seldom easy, but it’s even more difficult when their supply chains are highly dissimilar, says Jim Calarese, director of supply chain systems at Sanofi Genzyme.

The pharmaceutical company is the result of a takeover by Sanofi in 2001. The parent company’s supply chain was “plant-centric,” Calarese says. By contrast, Genzyme’s was completely end-to-end in nature. “Theirs was easier than ours.”

No pharmaceutical supply chain is without its challenges. Typically, supply chains are extended, lead times are long and a thicket of government regulations combine to present some steep challenges. Genzyme had diligently worked to have a total view of its supply chain as it developed and marketed drugs for rare diseases, multiple sclerosis, and oncology and immunology markets.

Sanofi Genzyme: Trends in Pharmaceutical Supply Chains

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The 5 ‘C’s’ for CMO Relationships in Pharmaceutical Supply Chain

BillDuBois

Pharmaceutical supply chainI recently attended the LogiPharma conference in Princeton, NJ to hear a number of speakers give their thoughts on the state of the pharmaceutical supply chain. Of particular interest was a session on Contract Manufacturing Operations (CMO) relationships with Michael Daly, Director of Supply Chain for Valeant Pharmaceuticals. He talked about the 5 C’s for a CMO relationship in pharma.

There was agreement among many at the conference that pharma is a bit behind the high tech and automotive industries when it comes to supply chain efficiencies. To their credit, those same individuals acknowledged they were looking to other industries for best practices. High tech and automotive have long realized they could drive efficiencies up and costs down by not doing everything from scratch.

In many cases within high tech and automotive, the leaders in supplier relationships have developed interactive supplier engagements that allow for easy communication between customer and supplier. These improved supplier relationships have enabled the easy sharing of purchase order information, forecast requests and the ability to initiate collaborative reviews and adjustments. It’s become easier for the Original Equipment Manufacturer (OEM) to track supplier commitments and get alerts to gaps between request and commit dates, so action can be taken to avoid shortage conditions.

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State of the Pharmaceutical Supply Chain: Key Takeaways from LogiPharma US 2016

Dr. MadhavDurbha

Pharmaceutical Supply ChainPart of what makes my job very exciting is attending conferences. These events provide great opportunities to share, learn, network, and have fun. Earlier this week, I attended the LogiPharma conference, a wonderful event for supply chain professionals working in the pharmaceutical industry. Apart from taking part in numerous interactive presentations and roundtables, I had the opportunity to host a luncheon alongside my colleague, Bill Dubois, for a packed room of pharmaceutical industry executives and SCM practitioners.

All-in-all, it was a great validation of my point of view about where the pharma industry is with regards to its supply chain challenges, maturity and where it needs to go. In this blog, I want to share some key challenges faced by the pharma industry and pharmaceutical supply chains. And, in a future blog I will share some recommendations in light of these challenges:

1. Revenue pressures: With several blockbuster drug patents expiring (a.k.a. “patent cliff”) and with patent extensions harder to come by, large pharma companies are looking for opportunities to unlock additional value within their enterprises and across the value network as revenues remain under pressure.

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Kinaxis life sciences newsletter: Featuring complimentary analyst case study report on Amgen

MelissaClow

We are in the final days for offering complimentary access to the Kinaxis life sciences newsletter, which includes a Gartner Case Study: How Amgen Reinvigorated Its Supply Planning Process (Barry Blake, Hussain Mooraj: May 18, 2011).  According to the Gartner Case study, long supply cycle times require life science manufacturers to balance supply commitments, capacity management and product […]

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Kinaxis life sciences newsletter: Featuring complimentary analyst case study report on Amgen

MelissaClow

We recently produced a newsletter which includes complimentary access to a 6-page Gartner report titled Case Study: How Amgen Reinvigorated Its Supply Planning Process (Barry Blake, Hussain Mooraj: May 18, 2011) This Case Study provides insights on how Amgen transformed its supply planning processes and enabled rapid planning capabilities, with advanced planning capabilities and systems. […]

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Cross industry knowledge transfer: Can lessons learned in Pharma apply to product obsolescence in High Tech Electronics?

MartinBuckley

I was talking to another consultant recently about issues one of their customers had with obsolescence in the high tech electronics industry. He said with all the rapid advances in technology, it is becoming increasingly difficult to avoid the effects of product obsolescence and its effects on margins, scrap, and inventory levels. He asked me […]

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